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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
38.48
Human Site:
Y522
Identified Species:
70.56
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
Y522
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
Y520
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
Y494
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Dog
Lupus familis
XP_543425
664
72715
Y595
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
Y522
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Rat
Rattus norvegicus
Q66H76
586
64001
Y517
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
Y490
F
E
H
D
G
Q
P
Y
C
E
V
H
Y
H
E
Frog
Xenopus laevis
Q2TCH4
506
55983
L449
Y
H
S
R
R
G
S
L
C
A
G
C
E
Q
P
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
C362
E
K
M
F
G
T
K
C
H
G
C
D
F
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
Y512
F
D
H
E
G
L
P
Y
C
E
T
H
Y
H
A
Honey Bee
Apis mellifera
XP_624308
559
62451
Y490
F
D
H
E
G
L
P
Y
C
E
T
H
Y
H
A
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
C356
R
G
S
I
C
S
Q
C
R
G
A
I
N
G
R
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
Y626
F
D
H
D
G
V
P
Y
C
E
I
H
Y
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
6.6
N.A.
66.6
66.6
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
20
N.A.
80
80
0
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
24
% A
% Cys:
0
0
0
0
8
0
0
16
85
0
8
8
0
0
0
% C
% Asp:
0
24
0
62
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
54
0
16
0
0
0
0
0
77
0
0
8
0
54
% E
% Phe:
77
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
85
8
0
0
0
16
8
0
0
8
0
% G
% His:
0
8
77
0
0
0
0
0
8
0
0
77
0
77
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
8
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
16
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
54
8
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
0
16
0
0
8
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
54
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
77
0
0
0
0
77
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _